DNA sequence of mutations induced in cells by herpes simplex virus type-1.

doi:10.1016/0042-6822(90)90392-5

Back to search

Article

DNA sequence of mutations induced in cells by herpes simplex virus type-1.

Virology - 1 Sept 1990

Hwang C B, Shillitoe E J

Abstract excerpt

The shuttle vector plasmid pZ189 was used to find the kinds of mutations that are induced in cells by herpes simplex virus type-1 (HSV-1). A significant increase in mutation frequency was detected as early as 2 hr after infection, and reached a peak of two- to sevenfold over background at 4 hr af...

Topics

Animals
Base Sequence
Cells, Cultured
Chromosome Deletion
DNA, Viral
Gene Frequency
Herpes Simplex
Molecular Sequence Data
Mutation
Plasmids
Simplexvirus

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.