Article
DNA sequence of mutations induced in cells by herpes simplex virus type-1.
Virology - 1 Sept 1990
Hwang C B, Shillitoe E J
Abstract excerpt
The shuttle vector plasmid pZ189 was used to find the kinds of mutations that are induced in cells by herpes simplex virus type-1 (HSV-1). A significant increase in mutation frequency was detected as early as 2 hr after infection, and reached a peak of two- to sevenfold over background at 4 hr after infection. Several differences were detected between spontaneous mutants and those induced by HSV-1 when they were...
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