A new marker in the HLA class I region is associated with the age at onset of IDDM.

doi:10.1007/BF00400734

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Article

A new marker in the HLA class I region is associated with the age at onset of IDDM.

Diabetologia - 1 May 1995

Demaine A G, Hibberd M L, Mangles D, Millward B A

Abstract excerpt

The (MHC) class II association with insulin-dependent diabetes mellitus (IDDM) is well documented. However, it is likely that genes within the MHC class III and the class I region also play a role in determining susceptibility to IDDM. In this study we have used a novel molecular probe to investi...

Topics

Adolescent
Adult
Age of Onset
Cell Line
Centromere
Child
Chromosome Mapping
Chromosomes, Artificial, Yeast
DNA Probes
Diabetes Mellitus, Type 1
Disease Susceptibility
Gene Frequency
Genes, MHC Class I
Genetic Predisposition to Disease
Genotype
HLA-A Antigens
HLA-B Antigens
Histocompatibility Antigens Class I

Source

Open in PubMed

Identifiers

PMID: 7489848
DOI: 10.1007/BF00400734

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-7489848-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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