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Article

Prevalence of HLA-DQ beta chain non-Asp alleles in type I (insulin-dependent) diabetics with young and older ages of onset.

Klinische Wochenschrift - 2 Oct 1991

Boehm B O, Scherbaum W A, Schöffling K, Kühnl P, Althoff P, Manfras B, Usadel K H, Trucco M

Abstract excerpt

Particular HLA-DQ beta chain alleles were reported as immunogenetic markers of type I diabetes mellitus with young onset of the disease. In a homogeneous German population, we studied HLA-DR specificities and HLA-DQ beta chain alleles in young-onset (less than 21 years of age; n = 185) and adult-onset (greater than 40 years of age; n = 48) insulin-dependent diabetics. In both cohorts of type I diabetics, the...

Topics

Adolescent
Adult
Alleles
Aspartic Acid
Chi-Square Distribution
Child
Child, Preschool
Diabetes Mellitus, Type 1
Female
HLA-DQ Antigens
HLA-DR3 Antigen

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

HLA-DR4 Antigen

Humans

Male

Middle Aged

Source

Identifiers

PMID: 1795491
DOI: 10.1007/BF01649437

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1795491-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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