Article
Prevalence of HLA-DQ beta chain non-Asp alleles in type I (insulin-dependent) diabetics with young and older ages of onset.
Klinische Wochenschrift - 2 Oct 1991
Boehm B O, Scherbaum W A, Schöffling K, Kühnl P, Althoff P, Manfras B, Usadel K H, Trucco M
Abstract excerpt
Particular HLA-DQ beta chain alleles were reported as immunogenetic markers of type I diabetes mellitus with young onset of the disease. In a homogeneous German population, we studied HLA-DR specificities and HLA-DQ beta chain alleles in young-onset (less than 21 years of age; n = 185) and adult-onset (greater than 40 years of age; n = 48) insulin-dependent diabetics. In both cohorts of type I diabetics, the...
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