Article
Cell cycle checkpoints and repair of ionizing radiation damage.
Stem cells (Dayton, Ohio) - 1 May 1995
Liu V F, Boubnov N V, Weaver D T
Abstract excerpt
Following exposure to ionizing radiation (IR), normal cells activate a delay in any phase of the cell cycle in conjunction with DNA repair mechanisms. Cell cycle delay or arrest is a programmed response that is mutable by a variety of genetic changes. DNA repair mechanisms that are responsible fo...
Topics
- Animals
- Antigens, Nuclear
- Autoantigens
- Biomarkers
- Cell Cycle
- DNA Damage
- DNA Helicases
- DNA Repair
- DNA-Binding Proteins
- G1 Phase
- Genes, p53
- Humans
- Ku Autoantigen
- Mice
- Mice, SCID
- Mutation
- Nuclear Proteins
- Phosphorylation