Article
Cell cycle checkpoints and repair of ionizing radiation damage.
Stem cells (Dayton, Ohio) - 1 May 1995
Liu V F, Boubnov N V, Weaver D T
Abstract excerpt
Following exposure to ionizing radiation (IR), normal cells activate a delay in any phase of the cell cycle in conjunction with DNA repair mechanisms. Cell cycle delay or arrest is a programmed response that is mutable by a variety of genetic changes. DNA repair mechanisms that are responsible for the repair of otherwise lethal IR-induced double-strand breaks (DSBs) operate in a parallel pathway. The formulation...
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