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Article

Cell cycle control, DNA damage checkpoints and cancer.

Annals of medicine - 1 Jan 2003

Laiho Marikki, Latonen Leena

Abstract excerpt

DNA damage checkpoints are essential control points in the cell cycle ensuring effective damage repair. The loss of checkpoint functions leads to loss of genomic integrity and allows accumulation of genetic damage in the daughter cells. Checkpoint deficiency is one of the main causes of DNA aberrations in cancer.

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Identifiers

PMID: 14572162
DOI: 10.1080/07853890310014605

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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