Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

G1 and S-phase checkpoints, chromosome instability, and cancer.

Methods in molecular biology (Clifton, N.J.) - 1 Jan 2004

Nojima Hiroshi

Abstract excerpt

Mitogen-dependent progression through the first gap phase (G1) of the mammalian cell-division cycle is precisely regulated so that normal cell division is coordinated with cell growth, while the initiation of DNA synthesis (S phase) is precisely ordered to prevent inappropriate amplification of the DNA that may cause genome instability. To ensure that these fundamental requirements of cell division are met, cells...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cell Cycle
Share to Cell Cycle Proteins
Share to Chromosomal Instability

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DNA Damage

Share to DNA Replication

Share to G1 Phase

Share to Neoplasms

Share to S Phase

Source

Identifiers

PMID: 15187248
DOI: 10.1385/1-59259-788-2:003

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

G1 and S-phase checkpoints, chromosome instability, and cancer.PMID 15187248Read ↗

Cell cycle checkpoint control mechanisms that can be disrupted in cancer.Semantic proximity Read ↗

Cell cycle checkpoints and their inactivation in human cancerSemantic proximity Read ↗

Cell cycle control, checkpoint mechanisms, and genotoxic stress.Semantic proximity Read ↗

DNA damage and cell cycle checkpointsSemantic proximity Read ↗

Cell cycle control, DNA damage checkpoints and cancer.Semantic proximity Read ↗

DNA damage checkpoints and cancer.Semantic proximity Read ↗

Mitotic checkpoints, genetic instability, and cancer.Semantic proximity Read ↗

Chromosome integrity checkpoints in stem and progenitor cells: transitions upon differentiation, pathogenesis, and agingSemantic proximity Read ↗

The G2 DNA damage checkpoint: Could this ancient regulator be the Achilles heel of cancer?Semantic proximity Read ↗

Defects in a cell cycle checkpoint may be responsible for the genomic instability of cancer cells.Semantic proximity Read ↗

MECHANISMS OF CELL-CYCLE CHECKPOINTS: AT THE CROSSROADS OF CARCINOGENESIS AND DRUG DISCOVERY*Semantic proximity Read ↗

Cell cycle checkpoints, genetic instability and cancer.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.