Apolipoprotein E epsilon 4 allele and the lifetime risk of Alzheimer's disease. What physicians know, and what they should know.

doi:10.1001/archneur.1995.00540350068018

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Article

Apolipoprotein E epsilon 4 allele and the lifetime risk of Alzheimer's disease. What physicians know, and what they should know.

Archives of neurology - 1 Nov 1995

Seshadri S, Drachman D A, Lippa C F

Abstract excerpt

BACKGROUND: Published studies now show a clear association between Alzheimer's disease (AD) and the apolipoprotein E epsilon 4 allele (APOE* epsilon 4). The clinical value of this information to estimate a healthy individual's lifetime risk of AD has not been well delineated. Physicians dealing w...

Topics

Actuarial Analysis
Adult
Aged
Alleles
Alzheimer Disease
Apolipoprotein E4
Apolipoproteins E
Bayes Theorem
Humans
Risk Factors

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