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Article

Pattern of usage of the VH4-21 gene by B lymphocytes in a patient with EBV infection indicates ongoing mutation and class switching.

Annals of the New York Academy of Sciences - 29 Sept 1995

Chapman C, Spellerberg M, Hamblin T, Stevenson F

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Share to B-Lymphocytes
Share to Cell Line
Share to DNA Mutational Analysis
Share to Herpesvirus 4, Human

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Immunoglobulin Class Switching

Share to Immunoglobulin Heavy Chains

Share to Immunoglobulin Variable Region

Share to Polymerase Chain Reaction

Source

Identifiers

PMID: 7486524
DOI: 10.1111/j.1749-6632.1995.tb55827.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Pattern of usage of the VH4-21 gene by B lymphocytes in a patient with EBV infection indicates ongoing mutation and class switching.PMID 7486524Read ↗

Pattern of usage of the VH4-21 gene by B lymphocytes in a patient with EBV infection indicates ongoing mutation and class switching.Semantic proximity Read ↗

Utilization of the VH4-21 Gene Segment by Anti-DNA Antibodies from Patients with Systemic Lupus ErythematosusSemantic proximity Read ↗

Tracking of the V4-34 (VH4-21) gene in human tonsil reveals clonal isotype switch events and a highly variable degree of somatic hypermutation.Semantic proximity Read ↗

Strikingly homologous immunoglobulin gene rearrangements and poor outcome in VH3-21-using chronic lymphocytic leukemia patients independent of geographic origin and mutational status.Semantic proximity Read ↗

Analysis of VH genes used by neoplastic B cells in endemic Burkitt's lymphoma shows somatic hypermutation and intraclonal heterogeneity.Semantic proximity Read ↗

Preferred usage of specific immunoglobulin gene segments in chronic lymphocytic leukaemia cells of three HLA-identical sisters.Semantic proximity Read ↗

V(H)3-21 gene usage in chronic lymphocytic leukemia--characterization of a new subgroup with distinct molecular features and poor survival.Semantic proximity Read ↗

Chronic lymphocytic leukemias utilizing the VH3-21 gene display highly restricted Vlambda2-14 gene use and homologous CDR3s: implicating recognition of a common antigen epitope.Semantic proximity Read ↗

Human anti-Gal heavy chain genes. Preferential use of VH3 and the presence of somatic mutations.Semantic proximity Read ↗

B lymphocyte selection and age-related changes in VH gene usage in mutant Alicia rabbits.Semantic proximity Read ↗

Geographic patterns and pathogenetic implications of IGHV gene usage in chronic lymphocytic leukemia: the lesson of the IGHV3-21 geneSemantic proximity Read ↗

Mutated VH genes and preferential VH3-21 use define new subsets of mantle cell lymphoma.Semantic proximity Read ↗

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