Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Behavioral effects and pharmacokinetics of propofol in rats selected for differential ethanol sensitivity.

Alcoholism, clinical and experimental research - 1 Aug 1995

Liu Y, Fay T, Deitrich R A

Abstract excerpt

High- and low-alcohol sensitivity (HAS and LAS) rats have been selected for their differences in ethanol-induced sleep time. The rats also differ in sensitivity to pentobarbital, halothane, isoflurane, and enflurane. To determine if this sensitivity extended to propofol, the anesthetic requirements were measured. In this study, the sleep time and the tissue levels of propofol at awakening, as well as the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Rats, Inbred Strains
Share to Alcoholism
Share to Metabolic Clearance Rate

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Phenotype

Share to Selection, Genetic

Share to Sleep Stages

Source

Identifiers

PMID: 7485833
DOI: 10.1111/j.1530-0277.1995.tb00961.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Behavioral effects and pharmacokinetics of propofol in rats selected for differential ethanol sensitivity.PMID 7485833Read ↗

Differences in hepatic microsomal cytochrome P-450 isoenzyme induction by pyrazole, chronic ethanol, 3-methylcholanthrene, and phenobarbital in high alcohol sensitivity (HAS) and low alcohol sensitivity (LAS) rats.Semantic proximity Read ↗

Ethanol interoceptive cue and sleep-time duration in HAS and LAS selectively bred rats.Semantic proximity Read ↗

Selective breeding of rats differing in sensitivity to the effects of acute ethanol administration.Semantic proximity Read ↗

gamma-Aminobutyric acid-activated chloride channels in rats selectively bred for differential acute sensitivity to alcohol.Semantic proximity Read ↗

Synaptic membrane responses to acute and chronic alcohol intoxication in high alcohol sensitive (HAS) and low alcohol sensitive (LAS) selectively bred rats.Semantic proximity Read ↗

Cardiovascular effects of ethanol in rats selectively bred for high or low sensitivity to the hypnotic effects of ethanol.Semantic proximity Read ↗

Tolerance and dependence in high alcohol sensitivity (HAS) and low alcohol sensitivity (LAS) rats after chronic alcohol intoxication by inhalation.Semantic proximity Read ↗

Genetic covariation in low alcohol-sensitive and high alcohol-sensitive selected lines of rats: behavioral and electrophysiological sensitivities to the depressant effects of ethanol and the development of acute neuronal tolerance to ethanol in situ at generation eight.Semantic proximity Read ↗

Identification of a genetic region in mice that specifies sensitivity to propofol.Semantic proximity Read ↗

Intermittent short- and long-term alcohol exposures influence alcohol consumption, anxiety-like behaviors, and seizure onset in genetically epilepsy-prone rats.Semantic proximity Read ↗

Inverse genetic association between alcohol preference and severity of alcohol withdrawal in two sets of rat lines selected for the same phenotype.Semantic proximity Read ↗

Quantitative trait locus analyses of sleep-times induced by sedative-hypnotics in LSXSS recombinant inbred strains of mice.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.