Article
Selective breeding of rats differing in sensitivity to the effects of acute ethanol administration.
Alcoholism, clinical and experimental research - 1 Feb 1992
Draski L J, Spuhler K P, Erwin V G, Baker R C, Deitrich R A
Abstract excerpt
Selective breeding of rats for sensitivity to the anesthetic effects of ethanol is being carried out with rats derived from the genetically heterogeneous N/Nih stock. Thirteen generations of within family selection have been achieved with replicate high (HAS), low (LAS) and control alcohol sensitive (CAS) lines. Significant separation between lines on sleep time and blood ethanol concentration (BEC) at awakening...
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