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Article

Ethanol interoceptive cue and sleep-time duration in HAS and LAS selectively bred rats.

Pharmacology, biochemistry, and behavior - 1 Jun 1990

Krimmer E C

Abstract excerpt

The drug discrimination paradigm was used to evaluate the effects of selective breeding for differential sensitivity to the hypnotic effects of ethanol. Tenth generation high alcohol sensitive (HAS) and low alcohol sensitive (LAS) rats were trained to discriminate between ethanol (0.6 g/kg, IP) and saline vehicle on a VR-5 schedule of reinforcement. The animals were tested with 0.15, 0.3, and 0.9 g/kg ethanol...

Topics

Animals
Breeding
Cues
Discrimination Learning
Ethanol
Hypnotics and Sedatives
Male
Phenotype
Rats
Sleep
Species Specificity
Time Factors

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 2356197
DOI: 10.1016/0091-3057(90)90400-c

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-2356197-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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