Article
Quantitative trait locus analyses of sleep-times induced by sedative-hypnotics in LSXSS recombinant inbred strains of mice.
Alcoholism, clinical and experimental research - 1 May 1996
Christensen S C, Johnson T E, Markel P D, Clark V J, Fulker D W, Corley R P, Collins A C, Wehner J M
Abstract excerpt
The long-sleep (LS) and short-sleep (SS) selected lines of mice show highly significant differences in sleep-time for many sedative-hypnotic drugs, and the quantitative genetic nature of these differences has been well-established. Using an interval-mapping approach, quantitative trait locus (QTL) analyses of LSXSS recombinant inbred (RI) strains have been applied to sleep-time responses for various classes of...
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