Article
Quantitative trait locus analyses of sleep-times induced by sedative-hypnotics in LSXSS recombinant inbred strains of mice.
Alcoholism, clinical and experimental research - 1 May 1996
Christensen S C, Johnson T E, Markel P D, Clark V J, Fulker D W, Corley R P, Collins A C, Wehner J M
Abstract excerpt
The long-sleep (LS) and short-sleep (SS) selected lines of mice show highly significant differences in sleep-time for many sedative-hypnotic drugs, and the quantitative genetic nature of these differences has been well-established. Using an interval-mapping approach, quantitative trait locus (QTL...
Topics
- 1-Butanol
- 1-Propanol
- Animals
- Anti-Anxiety Agents
- Barbiturates
- Benzodiazepines
- Butanols
- Chloral Hydrate
- Chromosome Mapping
- Ethanol
- Female
- Hypnotics and Sedatives
- Male
- Mice
- Mice, Inbred Strains
- Phenotype
- Recombination, Genetic
- Sleep Stages