Article
Cardiovascular effects of ethanol in rats selectively bred for high or low sensitivity to the hypnotic effects of ethanol.
Alcoholism, clinical and experimental research - 1 Sept 1997
Varga K, Kunos G
Abstract excerpt
The cardiovascular effects of acute ethanol administration were studied in rats selectively bred for high (HAS) or low sensitivity (LAS) to the acute hypnotic effect of ethanol. In chronically cannulated, conscious animals, the intravenous administration of 1 g/kg of ethanol caused moderate hypotension and tachycardia in both HAS and LAS rats. The phenylephrine-induced reflex bradycardia and the baroreflex slope...
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