Genetic covariation in low alcohol-sensitive and high alcohol-sensitive selected lines of rats: behavioral and electrophysiological sensitivities to the depressant effects of ethanol and the development of acute neuronal tolerance to ethanol in situ at generation eight.

Abstract excerpt

Phenotypic differences in behavioral and initial neuronal sensitivities to acute ethanol (EtOH) administration were examined and compared among replicate lines of rats, which were selectively bred for low and high EtOH sensitivity. The eighth generation of HAS (EtOH-sensitive) and LAS (EtOH-insen...

Topics

• Action Potentials
• Animals
• Behavior, Animal
• Drug Tolerance
• Ethanol
• Phenotype
• Purkinje Cells
• Rats
• Sleep
• Species Specificity