Article
Tolerance and dependence in high alcohol sensitivity (HAS) and low alcohol sensitivity (LAS) rats after chronic alcohol intoxication by inhalation.
Alcohol and alcoholism (Oxford, Oxfordshire) - 1 Jul 1994
Aufrère G, Ménez J F, Beaugé F, Duffy O, Le Bourhis B
Abstract excerpt
In rats selected for their differences in sleep time following acute administration of ethanol (high or low alcohol sensitivity: HAS or LAS), alcohol chronic tolerance and behavioural dependence were determined. Tolerance was assessed by calculating the interval between the loss and regain of the...
Topics
- Administration, Inhalation
- Alcoholic Intoxication
- Alcoholism
- Animals
- Body Weight
- Drug Tolerance
- Ethanol
- Male
- Phenotype
- Postural Balance
- Rats
- Rats, Inbred Strains
- Selection, Genetic
- Sleep Stages
