Article
Low rate of somatic hypermutations characterize progressive B-cell lymphomas.
European journal of haematology - 1 Sept 1998
Rosenquist R, Lindström A, Li A H, Roos G, Lindh J, Holmberg D
Abstract excerpt
Immunoglobulin heavy (IgH) chain gene rearrangements were characterized in 40 samples from 15 patients with B-cell lymphomas at different time points during tumour progression. Using polymerase chain reaction (PCR) amplification and single strand conformation polymorphism (SSCP) analysis of varia...
Topics
- Adult
- Aged
- Base Sequence
- Female
- Gene Rearrangement, B-Lymphocyte
- Humans
- Immunoglobulin Heavy Chains
- Lymphoma, B-Cell
- Male
- Middle Aged
- Molecular Sequence Data
- Mutation