Comparison of the X-gal- and P-gal-based systems for screening of mutant lambda lacZ phages originating from the transgenic mouse strain 40.6.

doi:10.1016/0165-1161(96)00004-0

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Article

Comparison of the X-gal- and P-gal-based systems for screening of mutant lambda lacZ phages originating from the transgenic mouse strain 40.6.

Mutation research - 10 Jun 1996

Mientjes E J, Steenwinkel M J, van Delft J H, Lohman P H, Baan R A

Abstract excerpt

The recent introduction of the phenyl-beta-D-galactopyranoside (P-gal)-based positive-selection system for screening of lambda lacZ phages originating from the lambda lacZ transgenic mouse (Muta Mouse) has made the determination of mutant frequencies (MF) a much simpler task. Previously, MF data...

Topics

Animals
Bacteriophage lambda
Benzo(a)pyrene
Brain
Ethylnitrosourea
Galactosides
Indoles
Liver
Mice
Mice, Transgenic
Mutagens
Mutation

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