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Article

A method for the isolation of longevity mutants in the nematode Caenorhabditis elegans and initial results.

Mechanisms of ageing and development - 1 Jan 2000

Klass M R

Abstract excerpt

The free-living nematode Caenorhabditis elegans is used as a genetically manipulable experimental system for the study of aging. Utilizing a temperature-sensitive sterile strain with a normal life span, a method is described for the isolation of mutant strains with significantly increased life spans. Eight mutant strains were isolated each having increased life spans. Two mutant strains were spontaneous dauer...

Topics

Aging
Animals
Caenorhabditis
Chemotaxis
Digestion
Genes
Longevity
Mutation
Pharynx

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 6632998
DOI: 10.1016/0047-6374(83)90082-9

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-6632998-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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