Using Caenorhabditis elegans as a model for aging and age-related diseases.

doi:10.1196/annals.1354.015

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Article

Using Caenorhabditis elegans as a model for aging and age-related diseases.

Annals of the New York Academy of Sciences - 1 May 2006

Olsen Anders, Vantipalli Maithili C, Lithgow Gordon J

Abstract excerpt

During the last three decades the soil nematode C. elegans has become a prominent model organism for studying aging. Initially research in the C. elegans aging field was focused on the genetics of aging and single gene mutations that dramatically increased the life span of the worm. Undoubtedly, the existence of such mutations is one of the main reasons for the popularity of the worm as model system for studying...

Topics

Aging
Animals
Caenorhabditis elegans
Disease Models, Animal
Genes, Helminth
Longevity
Mutation
Oxidative Stress

Source

Open in PubMed

Identifiers

PMID: 16803977
DOI: 10.1196/annals.1354.015

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