Article
Codon equilibrium I: Testing for homogeneous equilibrium.
Journal of molecular evolution - 1 Jan 2000
Wilbur W J
Abstract excerpt
We present theoretical considerations that suggest that synonymous-codon usage might be expected to be close to an equilibrium distribution given a very homogeneous process of silent substitution. By homogeneous we mean that substitution depends only on the two bases involved, so that 12 base-substitution rates completely describe the silent substitution process. We have developed a method of statistically...
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