Article
Selection, mutations and codon usage in a bacterial model.
Journal of theoretical biology - 7 Apr 1995
Bagnoli F, Liò P
Abstract excerpt
We present a statistical model of bacterial evolution based on the coupling between codon usage and tRNA abundance. Such a model interprets this aspect of the evolutionary process as a balance between the codon homogenization effect due to mutation process and the improvement of the translation phase due to natural selection. We develop a thermodynamical description of the asymptotic state of the model. The...
Topics
- Bacteria
- Biological Evolution
- Codon
- Models, Genetic
- Models, Statistical
- Mutation
