Article
Mutagens in rat urine after dermal application of 1,3-diaminobenzene.
Mutation research - 1 Jan 2000
Clemmensen S, Lam H R
Abstract excerpt
The mutagenicity of urine from rats treated topically on the skin with 1,3-diaminobenzene was studied by the Salmonella/mammalian-microsome assay. Urine samples were either passed directly through micropore filters or extracts were prepared using XAD-2 resin before testing in the frameshift strain TA98. Significant mutagenic activity was found only after metabolic activation with rat-liver microsomes. The...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
