Article
4-Chloromethylbiphenyl (4CMB), benzyl chloride (BC) and 4-hydroxymethylbiphenyl (4HMB): an evaluation of their mutagenic potential using Salmonella typhimurium.
Mutation research - 1 Jan 2000
Jones E, Richold M
Abstract excerpt
The 3 compounds 4CMB, BC and 4HMB were tested using the "Ames' Salmonella assay. 4CMB produced a strong mutagenic response; no evidence of mutagenic activity was obtained with BC and 4HMB. Urine from mice treated with the 3 compounds was also tested. None of the urine samples produced a mutagenic response.
Topics
- Animals
- Biotransformation
- Biphenyl Compounds
- Mice
- Mutagenicity Tests
- Mutagens
- Mutation
- Salmonella typhimurium
- Species Specificity
- Structure-Activity Relationship