Article
Mutagenicity studies on coffee. The influence of different factors on the mutagenic activity in the Salmonella/mammalian microsome assay.
Mutation research - 1 Jan 2000
Friederich U, Hann D, Albertini S, Schlatter C, Würgler F E
Abstract excerpt
Recently, mutagenic activity on several strains of Salmonella typhimurium has been found in many heat-processed foodstuffs. The previously reported direct-acting mutagenic activity of coffee in Salmonella typhimurium TA100 (Ames assay) was confirmed in our study. In addition to TA100, a mutagenic...
Topics
- Aldehydes
- Animals
- Biotransformation
- Coffee
- Gastric Juice
- Glutathione
- Glutathione Transferase
- Hydrogen-Ion Concentration
- Lactoylglutathione Lyase
- Male
- Microsomes, Liver
- Mutagenicity Tests
- Mutation
- Pyruvaldehyde
- Rats
- Salmonella typhimurium
- Temperature