Article
Mutagenesis assays on urines produced by patients administered adriamycin and cyclophosphamide.
Environmental and molecular mutagenesis - 1 Jan 1990
Newman M A, Hee S S, Schoeny R S
Abstract excerpt
The XAD-2 resin concentration/elution system for concentration of mutagens contained in urines was optimized for cancer patients who had been administered such antineoplastic agents as adriamycin (ADR; doxorubicin), cyclophosphamide (CP), methotrexate, vincristine, and 5-fluorouracil. In the reve...
Topics
- Animals
- Cyclophosphamide
- Doxorubicin
- Drug Therapy, Combination
- Glucuronidase
- Humans
- Kidney Neoplasms
- Liver Neoplasms
- Male
- Microsomes
- Mutagenicity Tests
- Mutation
- Rats
- Rats, Inbred Strains
- Salmonella
- Sulfatases