Article
Mutagenesis assays on urines produced by patients administered adriamycin and cyclophosphamide.
Environmental and molecular mutagenesis - 1 Jan 1990
Newman M A, Hee S S, Schoeny R S
Abstract excerpt
The XAD-2 resin concentration/elution system for concentration of mutagens contained in urines was optimized for cancer patients who had been administered such antineoplastic agents as adriamycin (ADR; doxorubicin), cyclophosphamide (CP), methotrexate, vincristine, and 5-fluorouracil. In the reverse mutation assay, Salmonella typhimurium strains TA1535 and TA98 differentiated between CP (with S9 fraction) and ADR...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
