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Article

Ultraviolet-irradiated simian virus 40 activates a mutator function in rat cells under conditions preventing viral DNA replication.

Biochimie - 1 Jan 2000

Cornelis J, Su Z Z, Dinsart C, Rommelaere J

Abstract excerpt

The UV-irradiated temperature-sensitive early SV40 mutant tsA209 is able to activate at the nonpermissive temperature the expression of mutator and recovery functions in rat cells. Unirradiated SV40 activates these functions only to a low extent. The expression of these mutator and recovery functions in SV40-infected cells was detected using the single-stranded DNA parvovirus H-1 as a probe. Because early SV40...

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PMID: 6291637
DOI: 10.1016/s0300-9084(82)80109-0

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