Article
Enhanced reactivation and mutagenesis after transfection of carcinogen-treated monkey kidney cells with UV-irradiated simian virus 40 (SV40) DNA.
Biochimie - 1 Jan 2000
Gentil A, Margot A, Sarasin A
Abstract excerpt
Monkey kidney cells, either untreated or pretreated with UV-light at 254 nm or mitomycin C, were transfected 24 hours later with the intact or UV-irradiated DNA from the thermosensitive tsB201 simian virus 40 mutant unable to grow at 41 degrees C. The survival of the viral progeny obtained from t...
Topics
- Animals
- Antibiotics, Antineoplastic
- Cell Line
- Chlorocebus aethiops
- DNA, Viral
- Kidney
- Mitomycin
- Mitomycins
- Mutation
- Simian virus 40
- Transfection
- Ultraviolet Rays
