Error-prone replication of ultraviolet-irradiated simian virus 40 in carcinogen-treated monkey kidney cells.

doi:10.1016/s0300-9084(82)80135-1

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Article

Error-prone replication of ultraviolet-irradiated simian virus 40 in carcinogen-treated monkey kidney cells.

Biochimie - 1 Jan 2000

Sarasin A, Bourre F, Benoit A

Abstract excerpt

To analyze the molecular mechanism of mutagenesis in carcinogen-treated mammalian cells, we developed a model system composed of various simian virus 40 (SV40) mutants as a biological probe to detect inducible DNA repair and mutagenesis in carcinogen-treated monkey kidney cells (CV1-P). Results h...

Topics

Animals
Cell Line
Cell Transformation, Viral
Chlorocebus aethiops
DNA Replication
DNA Restriction Enzymes
Mutation
Simian virus 40
Ultraviolet Rays
Viral Plaque Assay

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