Article
alpha-1-Antitrypsin phenotypes in hepatocellular carcinoma.
Hepatology (Baltimore, Md.) - 1 Jan 2000
Govindarajan S, Ashcavai M, Peters R L
Abstract excerpt
alpha-1-Antitrypsin deficiency due to homozygous Pi ZZ state is reported to be associated with cirrhosis and hepatocellular carcinoma (HCC); however, the role of heterozygous Pi Z state is not definitely known. In order to investigate the possible association, we studied the phenotypic distribution of alpha-1-antitrypsin variants (Pi) in 124 cases of HCC. Two thousand ten normal American Red Cross blood donors...
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