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Article

Is heterozygous alpha-1-antitrypsin deficiency type PIZ a risk factor for primary liver carcinoma?

Cancer - 15 Jun 2000

Zhou H, Ortiz-Pallardó M E, Ko Y, Fischer H P

Abstract excerpt

BACKGROUND: It is well known that homozygotes with alpha-1-antitrypsin deficiency type PiZ are associated with an increased risk of chronic liver disease and liver carcinoma. The aim of this study was to determine whether heterozygous PiZ status is a risk factor for liver carcinoma development. METHODS: Three hundred seventeen consecutive primary liver carcinomas and the tumor-bearing liver tissue (tumor series)...

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Source

Identifiers

PMID: 10870048
DOI: 10.1002/1097-0142(20000615)88:12<2668::aid-cncr4>3.0.co;2-g

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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