Lack of increase in heterozygous alpha 1-antitrypsin deficiency phenotypes among patients with hepatocellular and bile duct carcinoma.

doi:10.1002/hep.1840150309

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Article

Lack of increase in heterozygous alpha 1-antitrypsin deficiency phenotypes among patients with hepatocellular and bile duct carcinoma.

Hepatology (Baltimore, Md.) - 1 Mar 1992

Rabinovitz M, Gavaler J S, Kelly R H, Prieto M, Van Thiel D H

Abstract excerpt

Homozygous alpha 1-antitrypsin deficiency (PiZZ phenotype) is known to be associated with increased risk of cirrhosis and primary liver cancer. Although a relationship between heterozygous alpha 1-antitrypsin deficiency and chronic liver disease was suggested recently, it is still a matter of con...

Topics

Adenoma, Bile Duct
Carcinoma, Hepatocellular
Female
Heterozygote
Humans
Liver Neoplasms
Male
Phenotype
alpha 1-Antitrypsin
alpha 1-Antitrypsin Deficiency

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