Article
Association of α 1 Antitrypsin Phenotype and Development of Advanced Liver Disease and Pulmonary Complications Before and After Liver Transplantation.
Transplantation - 1 Jul 2021
Abu Rmilah Anan, Fencl Robert, Watt Kymberly, Krowka Michael, Wiesner Russell, Murray David, Nyberg Scott, Leise Michael
Abstract excerpt
BACKGROUND: The role of MZ phenotype of α 1 antitrypsin (α1AT) deficiency as a potential cofactor in advanced liver disease arising from other primary causes is not widely understood. In the general population, MZ phenotype accounts for 2%-4% in Europe and 2%-7.1% in North America. The aim of this study was to determine the prevalence of the MZ phenotype among various causes of cirrhosis in the United States in...
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