Article
alpha 1-antitrypsin phenotype PiMZ, a risk factor for liver cirrhosis but not for liver cancers in Thailand.
The Southeast Asian journal of tropical medicine and public health - 1 Jun 1995
Smanadhikorn P, Pongpaew P, Srivatanakul P, Tungtrongchitr R, Supanaranond W, Schelp F P, Migasena P
Abstract excerpt
The risk of developing liver cirrhosis, hepatoma (HCC) and bile duct carcinoma (BDC) have been associated with homozygous alpha 1-antitrypsin (AT) deficiency especially linked to the Z allele. While the association between liver cancers and AT deficiency remains debatable, the risk of adult AT deficiency carriers to develop liver cirrhosis has not been assessed quantitatively. Liver cancers and liver diseases...
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