Article
The p21 ras C-terminus is required for transformation and membrane association.
Nature - 1 Jan 2000
Willumsen B M, Christensen A, Hubbert N L, Papageorge A G, Lowy D R
Abstract excerpt
The Harvey murine sarcoma virus (Ha-MuSV) transforming gene, v-rasH, encodes a 21,000 molecular weight protein (p21) that is closely related to the p21 proteins encoded by the cellular transforming genes of the ras gene family. The primary translation product (prop21), which is found in the cytosol, undergoes posttranslational modification and the mature protein subsequently becomes associated with the inner...
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