Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Polygenic Risk Scores and Its Association With Cutaneous Melanoma Risk in the Swedish Population.

Pigment cell & melanoma research - 1 Sept 2026

Helgadottir Hildur, Yang Muyi, Cruz Ivette Raices, Schultz Karina, Höiom Veronica

Abstract excerpt

Polygenic risk scores can quantify an individual's genetic predisposition by combining the effects of multiple gene variants linked to melanoma susceptibility. Previous studies have demonstrated that PRS is strongly associated with melanoma risk and can improve the identification of high-risk individuals beyond that identified by traditional risk factors. The aim of this study was to calculate PRS for melanoma...

Read the complete abstract on PubMed

Topics

Humans
Melanoma
Sweden
Genetic Predisposition to Disease
Skin Neoplasms
Genetic Risk Score

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Polymorphism, Single Nucleotide

Female

Male

Middle Aged

Cutaneous Malignant Melanoma

Multifactorial Inheritance

Risk Factors

Case-Control Studies

Source

Open in PubMed Open full text

Identifiers

PMID: 42754918
DOI: 10.1111/pcmr.70118
PMCID: PMC13586051

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 25 Oct 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Polygenic Risk Scores and Its Association With Cutaneous Melanoma Risk in the Swedish Population.PMID 42754918Read ↗

Association between a 46-SNP Polygenic Risk Score and melanoma risk in Dutch patients with familial melanoma.Semantic proximity Read ↗

Combining common genetic variants and non-genetic risk factors to predict risk of cutaneous melanoma.Semantic proximity Read ↗

Genetics versus clinical risk scores for melanoma prediction.Semantic proximity Read ↗

Joint effect of multiple common SNPs predicts melanoma susceptibility.Semantic proximity Read ↗

Independent evaluation of melanoma polygenic risk scores in UK and Australian prospective cohorts.Semantic proximity Read ↗

Prediction of Melanoma Risk in a Southern European Population Based on a Weighted Genetic Risk Score.Semantic proximity Read ↗

Melanoma risk prediction based on a polygenic risk score and clinical risk factors.Semantic proximity Read ↗

Genome‐wide association studies and polygenic risk scores for skin cancer: clinically useful yet?Semantic proximity Read ↗

Recommendations for Primary Prevention of Skin MelanomaSemantic proximity Read ↗

Higher polygenic risk for melanoma is associated with improved survivalSemantic proximity Read ↗

Integrative genetic analysis suggests that skin color modifies the genetic architecture of melanoma.Semantic proximity Read ↗

Melanoma risk prediction using a multilocus genetic risk score in the Women's Health Initiative cohort.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.