Article
Integrative genetic analysis suggests that skin color modifies the genetic architecture of melanoma.
PloS one - 1 Jan 2017
Hulur Imge, Skol Andrew D, Gamazon Eric R, Cox Nancy J, Onel Kenan
Abstract excerpt
Melanoma is the deadliest form of skin cancer and presents a significant health care burden in many countries. In addition to ultraviolet radiation in sunlight, the main causal factor for melanoma, genetic factors also play an important role in melanoma susceptibility. Although genome-wide association studies have identified many single nucleotide polymorphisms associated with melanoma, little is known about the...
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