Melanoma risk prediction based on a polygenic risk score and clinical risk factors.

doi:10.1097/CMR.0000000000000896

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Article

Melanoma risk prediction based on a polygenic risk score and clinical risk factors.

Melanoma research - 1 Aug 2023

Wong Chi Kuen, Dite Gillian S, Spaeth Erika, Murphy Nicholas M, Allman Richard

Abstract excerpt

Melanoma is one of the most commonly diagnosed cancers in the Western world: third in Australia, fifth in the USA and sixth in the European Union. Predicting an individual's personal risk of developing melanoma may aid them in undertaking effective risk reduction measures. The objective of this study was to use the UK Biobank to predict the 10-year risk of melanoma using a newly developed polygenic risk score...

Topics

Humans
Melanoma
Risk Assessment
Skin Neoplasms
Risk Factors
Incidence
Genetic Predisposition to Disease
Genome-Wide Association Study

Source

Open in PubMed Open full text

Identifiers

PMID: 37096571
DOI: 10.1097/CMR.0000000000000896
PMCID: PMC10309112

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