Article
Scherer's map, remapped.
Cancer cell - 14 Sept 2026
Silver Daniel J, Xu Chang, Lathia Justin D
Abstract excerpt
Scherer's century-old classification of expansive and infiltrative glioma growth remains foundational to neuro-oncology. In this issue of Cancer Cell, Hoefflin et al. use spatial RNA and protein profiling of IDH-mutant gliomas to reveal hypoxia and necrosis as organizing centers of expansive growth and white-matter tracts as guides and constraints on invasion.
Read the complete abstract on PubMedTopics
- Humans
- Brain Neoplasms
- Glioma
- Isocitrate Dehydrogenase
- Animals
- Mutation
