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Article

Distribution of CYP2C19 polymorphism and predicted metabolizer phenotypes in the Indian population: A systematic review.

Indian journal of pharmacology - 1 Sept 2026

Singh Smriti, Goyal Chanchal, Patel Tejas K, Hada Vivek, Bhusal Chandra Kanta, Bhalla Hira Lal, Saurabh Manoj Kumar

Abstract excerpt

ABSTRACT: The distribution of CYP2C19 polymorphisms and associated metabolizer phenotypes varies across populations. There is a lack of large scale pooled data on CYP2C19 polymorphisms and associated metabolizer phenotypes in Indian population. This systematic review and meta analysis aimed to determine the prevalence of CYP2C19 loss of function and gain of function polymorphisms (*2, *3, and *17) and their...

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Topics

Cytochrome P-450 CYP2C19
Humans
India
Polymorphism, Genetic
Phenotype
Genotype

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

South Asian People

Source

Open in PubMed Open full text

Identifiers

PMID: 42683981
DOI: 10.4103/ijp.ijp_285_26
PMCID: PMC13610760

Genes

CYP2C19

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 25 Oct 2026.

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