Article
Global distribution of CYP2C19 risk phenotypes affecting safety and effectiveness of medications.
The pharmacogenomics journal - 1 Apr 2021
Biswas Mohitosh
Abstract excerpt
Genetic variability of CYP2C19 may affect safety or efficacy of many clinically important medications as outlined in the clinical pharmacogenetics implementation consortium (CPIC) dosing guidelines. To determine the predictive prevalence of high-risk phenotypes due to CYP2C19 genetic variants collectively in the world population and to establish a correlation how the identified high-risk phenotypes may affect...
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