Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

High-Throughput Screening of L-Lactic Acid-Hyperproducing Bacillus coagulans Mutants Using an Automated Droplet Microfluidic Platform.

Journal of visualized experiments : JoVE - 28 Jul 2026

Da Xin, Li Shuang, Wang Qingyuan, Luo Xunxun, Geng Dezhi, Guo Xiaojie, Wang Liyan, Jiang Dongliang, Wang Yi, Xing Xin-Hui, Xue Zhenglian, Zhang Chong

Abstract excerpt

Industrial biomanufacturing relies on microorganisms to efficiently synthesize target products under engineered conditions. However, wild-type strains often lack the capability to do so due to their native metabolic networks. Therefore, the rapid and accurate screening of high-performance strains from large-scale mutant libraries is a critical step in industrial microbial breeding. In recent years, droplet...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to High-Throughput Screening Assays
Share to Lactic Acid

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Microfluidic Analytical Techniques

Share to Mutation

Source

Identifiers

PMID: 42612135
DOI: 10.3791/71458

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

High-Throughput Screening of L-Lactic Acid-Hyperproducing Bacillus coagulans Mutants Using an Automated Droplet Microfluidic Platform.PMID 42612135Read ↗

High-throughput screening of filamentous fungi using nanoliter-range droplet-based microfluidics.Semantic proximity Read ↗

On-chip analysis, indexing and screening for chemical producing bacteria in a microfluidic static droplet array.Semantic proximity Read ↗

Finding the Needle in the Haystack-the Use of Microfluidic Droplet Technology to Identify Vitamin-Secreting Lactic Acid Bacteria.Semantic proximity Read ↗

Droplet-Based Microfluidic High-Throughput Screening of Enzyme Mutant Libraries Secreted by Yarrowia lipolytica.Semantic proximity Read ↗

A programmable droplet-based microfluidic device applied to multiparameter analysis of single microbes and microbial communities.Semantic proximity Read ↗

Microfluidic droplet platform for ultrahigh-throughput single-cell screening of biodiversity.Semantic proximity Read ↗

Recovery of phenotypically sorted cells using droplet-digital microfluidics.Semantic proximity Read ↗

Microfluidic screening and whole-genome sequencing identifies mutations associated with improved protein secretion by yeast.Semantic proximity Read ↗

Phenotyping and Selection of Cells Using Mass Spectrometry and a Microfluidic Droplet Printer.Semantic proximity Read ↗

RNA-aptamers-in-droplets (RAPID) high-throughput screening for secretory phenotypes.Semantic proximity Read ↗

CotA laccase: high-throughput manipulation and analysis of recombinant enzyme libraries expressed in E. coli using droplet-based microfluidics.Semantic proximity Read ↗

Droplet Tn-Seq combines microfluidics with Tn-Seq for identifying complex single-cell phenotypes.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.