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Article

High-throughput screening of filamentous fungi using nanoliter-range droplet-based microfluidics.

Scientific reports - 7 Jun 2016

Beneyton Thomas, Wijaya I Putu Mahendra, Postros Prexilia, Najah Majdi, Leblond Pascal, Couvent Angélique, Mayot Estelle, Griffiths Andrew D, Drevelle Antoine

Abstract excerpt

Filamentous fungi are an extremely important source of industrial enzymes because of their capacity to secrete large quantities of proteins. Currently, functional screening of fungi is associated with low throughput and high costs, which severely limits the discovery of novel enzymatic activities and better production strains. Here, we describe a nanoliter-range droplet-based microfluidic system specially adapted...

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PMID: 27270141
DOI: 10.1038/srep27223
PMCID: PMC4895158

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