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Article

A programmable droplet-based microfluidic device applied to multiparameter analysis of single microbes and microbial communities.

Proceedings of the National Academy of Sciences of the United States of America - 15 May 2012

Leung Kaston, Zahn Hans, Leaver Timothy, Konwar Kishori M, Hanson Niels W, Pagé Antoine P, Lo Chien-Chi, Chain Patrick S, Hallam Steven J, Hansen Carl L

Abstract excerpt

We present a programmable droplet-based microfluidic device that combines the reconfigurable flow-routing capabilities of integrated microvalve technology with the sample compartmentalization and dispersion-free transport that is inherent to droplets. The device allows for the execution of user-defined multistep reaction protocols in 95 individually addressable nanoliter-volume storage chambers by consecutively...

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Identifiers

PMID: 22547789
DOI: 10.1073/pnas.1106752109
PMCID: PMC3356603

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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