Association between the interleukin 17F rs763780 polymorphism and immune thrombocytopenia risk: A systematic review and meta-analysis.

doi:10.1016/j.cyto.2026.157199

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Article

Association between the interleukin 17F rs763780 polymorphism and immune thrombocytopenia risk: A systematic review and meta-analysis.

Cytokine - 1 Nov 2026

Fan Li, Huai Qingyang, Zhang Zheng, Liu Zhaikai, Zhang Xinyi, Wu Wencong, Ye He, Wang Shu, Zhao Zefan, Yang Xiaoqin, Wang Liya, Gao Shangshang

Abstract excerpt

The literature on the Interleukin 17F (IL-17F) rs763780 polymorphism and its association with immune thrombocytopenia (ITP) risk remains inconsistent and controversial. These uncertainties underscore the urgent need for a meta-analysis to objectively synthesize the heterogeneous findings, mitigate bias, and improve statistical power. This study strictly adhered to the Preferred Reporting Items for Systematic...

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Topics

Humans
Alleles
Case-Control Studies

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Genetic Association Studies

Genetic Predisposition to Disease

Interleukin-17

Odds Ratio

Polymorphism, Single Nucleotide

Purpura, Thrombocytopenic, Idiopathic

Risk Factors

Source

Open in PubMed

Identifiers

PMID: 42603394
DOI: 10.1016/j.cyto.2026.157199

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