Article
Decreased Frequency of IL-17F rs763780 Site Allele G is Associated With Genetic Susceptibility to Immune Thrombocytopenia in a Chinese Population.
Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis - 1 Jul 2017
Li Huiyuan, Zhou Zeping, Tai Wenlin, Feng Weiyang, Zhang Donglei, Gu Xueping, Yang Renchi
Abstract excerpt
Interleukin 17F (IL-17F) is an inflammatory cytokine that plays an important role in autoimmune disease by inducing the expression of multiple chemokines, cytokines, and adhesion molecules. In vitro functional analysis revealed that IL-17F rs763780 polymorphism is associated with IL-17 expression...
Topics
- Adolescent
- Adult
- Aged
- Asian People
- Child
- Child, Preschool
- China
- Female
- Gene Frequency
- Genetic Predisposition to Disease
- Humans
- Interleukin-17