Article
The interleukin-1 receptor antagonist gene VNTR polymorphism confers a genetic contribution to the risk of immune thrombocytopenia purpura: A systematic review and meta-analysis.
Cytokine - 1 Mar 2026
Wei Huifang, Xie Yuyang, Huai Qingyang, Hua Zixiao, Yang Xinyu, Chen Lingxi, Kong Youyi, Xue Wen, Zhao Caiming, Gao Shangshang, Yang Xiaoqin
Abstract excerpt
The purpose of this systematic review and meta-analysis was to summarize the existing evidence of the IL1RN variable number (usually two to six) of tandem repeat (VNTR) polymorphism in modulating the susceptibility to immune thrombocytopenia purpura (ITP), with the aim of clarifying its potential as a genetic marker for disease risk stratification. An extensive literature review was performed utilizing the...
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