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Article

The role of gene polymorphisms in the susceptibility and therapeutic response of chronic immune thrombocytopenic purpura.

Expert review of hematology - 1 May 2026

Moghaddasnejad Mohammad Reza, Aghaei Mojtaba, Saki Najmaldin

Abstract excerpt

INTRODUCTION: Chronic immune thrombocytopenic purpura (cITP) is a prolonged autoimmune disorder characterized by persistent low platelet counts and the presence of anti-platelet antibodies. The disease exhibits heterogeneity in severity and therapeutic response, which complicates management and underscores the importance of identifying predictive biomarkers. AREAS COVERED: This review examines gene polymorphisms...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Share to Genetic Predisposition to Disease

Share to Polymorphism, Genetic

Share to Purpura, Thrombocytopenic, Idiopathic

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Source

Identifiers

PMID: 41948789
DOI: 10.1080/17474086.2026.2636163

Genes

ABCB1
CXCL12
ICOS
IL10
IL6
TLR4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 24 Oct 2026.

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Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

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