IL-23/Th17 pathway and IL-17A gene polymorphism in Egyptian children with immune thrombocbytopenic purpura.

doi:10.1186/s13052-021-01131-3

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IL-23/Th17 pathway and IL-17A gene polymorphism in Egyptian children with immune thrombocbytopenic purpura.

Italian journal of pediatrics - 26 Aug 2021

Ismail Ahlam M, Higazi Aliaa M, Nomeir Hanan M, Farag Naglaa M

Abstract excerpt

BACKGROUND: Immune thrombocytopenic purpura (ITP) is an acquired complex autoimmune thrombocytopenia. Uncontrolled cellular immune response is one of the key triggers for the loss of immune tolerance in ITP patients. The purpose of this study was to investigate the association of IL-23/Th17, IL-17A and IL-17A rs2275913 gene polymorphism with ITP in Egyptian children. METHODS: 60 patients with ITP and 50 healthy...

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PMID: 34446083
DOI: 10.1186/s13052-021-01131-3
PMCID: PMC8394206

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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