IL-23/Th17 pathway and IL-17A gene polymorphism in Egyptian children with immune thrombocbytopenic purpura.

doi:10.1186/s13052-021-01131-3

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Article

IL-23/Th17 pathway and IL-17A gene polymorphism in Egyptian children with immune thrombocbytopenic purpura.

Italian journal of pediatrics - 26 Aug 2021

Ismail Ahlam M, Higazi Aliaa M, Nomeir Hanan M, Farag Naglaa M

Abstract excerpt

BACKGROUND: Immune thrombocytopenic purpura (ITP) is an acquired complex autoimmune thrombocytopenia. Uncontrolled cellular immune response is one of the key triggers for the loss of immune tolerance in ITP patients. The purpose of this study was to investigate the association of IL-23/Th17, IL-1...

Topics

Case-Control Studies
Child
Child, Preschool
Egypt
Female
Genotype
Humans
Infant
Interleukin-17
Interleukin-23
Male
Polymorphism, Genetic
Purpura, Thrombocytopenic, Idiopathic
Th17 Cells

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