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Article

Interleukin-17F gene polymorphism in patients with chronic immune thrombocytopenia.

European journal of haematology - 1 Sept 2011

Saitoh Takayuki, Tsukamoto Norifumi, Koiso Hiromi, Mitsui Takeki, Yokohama Akihiko, Handa Hiroshi, Karasawa Masamitsu, Ogawara Hatsue, Nojima Yoshihisa, Murakami Hirokazu

Abstract excerpt

INTRODUCTION: IL-17F is a novel inflammatory cytokine and plays an important role in some autoimmune diseases. We investigated the association between chronic ITP and the frequency of the single-nucleotide polymorphism rs763780 (7488T/C), which causes a His-to-Arg substitution at amino acid 161. PATIENTS AND METHODS: We examined 102 patients (men/women, 40/62; median age, 42) diagnosed with chronic ITP and 188...

Topics

Adolescent
Adult
Aged
Aged, 80 and over
Alleles
Case-Control Studies
Child
Female

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Gene Frequency

Genotype

Humans

Interleukin-17

Male

Middle Aged

Polymorphism, Genetic

Purpura, Thrombocytopenic, Idiopathic

Young Adult

Source

Identifiers

PMID: 21615796
DOI: 10.1111/j.1600-0609.2011.01651.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-21615796-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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