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Inflammation-Related Gene Polymorphisms Associated With Primary Immune Thrombocytopenia

28 Jun 2017

Abstract excerpt

Primary immune thrombocytopenia (ITP) is an acquired autoimmune disease characterized by a reduced platelet count and an increased risk of bleeding. Although immense research has improved our understanding of ITP, the pathogenesis remains unclear. Here, we investigated the involvement of 25 single nucleotide polymorphisms (SNPs) of the inflammation-related genes, including CD24, CD226, FCRL3, IL2, IRF5, ITGAM,...

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PMID: 28702029
DOI: 10.3389/fimmu.2017.00744

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